Question 1

What is Andes hantavirus (ANDV)?

Accepted Answer

Andes virus (ANDV) is a species of hantavirus that causes Hantavirus Cardiopulmonary Syndrome (HCPS), a severe and often fatal respiratory disease. It is the only hantavirus known to spread from person to person.

Question 2

How is Andes hantavirus transmitted?

Accepted Answer

ANDV is primarily transmitted by inhaling aerosolized virus from infected rodent urine, droppings, or saliva. Uniquely among hantaviruses, it can also spread person-to-person through close contact during the acute phase of illness.

Question 3

What are the symptoms of hantavirus infection?

Accepted Answer

Early symptoms include fever, severe muscle aches, headache, chills, and gastrointestinal issues. The disease can rapidly progress to cough, shortness of breath, and respiratory failure within days. The incubation period is 1-6 weeks.

Question 4

Is there a cure or vaccine for Andes hantavirus?

Accepted Answer

There is currently no approved antiviral drug or vaccine for Andes hantavirus. Treatment is supportive, including ICU care, mechanical ventilation, and in severe cases, ECMO. Early medical intervention significantly improves survival rates.

Question 5

What is the MV Hondius hantavirus outbreak?

Accepted Answer

The MV Hondius is a cruise ship operated by Oceanwide Expeditions. In April 2026, passengers were exposed to Andes hantavirus, likely during a visit to South Georgia Island. Two Dutch passengers died, and returned passengers are now being monitored across 15+ countries.

Question 6

What is the mortality rate of Andes hantavirus?

Accepted Answer

The case fatality rate for Hantavirus Cardiopulmonary Syndrome caused by Andes virus ranges from 30% to 40%. Early ICU intervention significantly improves survival. Patients who survive the acute phase generally recover fully.